Electrical stimulation of the bed nucleus of the stria terminalis reduces anxiety in a rat model
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چکیده
منابع مشابه
Can electrical stimulation of the human bed nucleus of the stria terminalis reduce contextual anxiety? An unanswered question
Citation: Luyck K and Luyten L (2015) Can electrical stimulation of the human bed nucleus of the stria terminalis reduce contextual anxiety? An unanswered question. In their paper, Baas et al. (2014), take the rather unique opportunity to conduct a human fear conditioning experiment in subjects with stimulation electrodes in the nucleus accumbens and internal capsule. Here, we argue that it mig...
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Introduction: Experiments were done to investigate the cardiovascular response to glutamate (Glu) injection in the bed nucleus of stria terminalis (BST) in urethane anesthetized ovariectomized (OVX) or OVX estrogen treated (OVX+E) female Wistar rats. In this study also the effect of glutaminergic system of the rostral ventrolateral medulla (RVLM) on Glu stimulation of cardiovascular...
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s | 3 reinstatement was accompanied by reduction of synaptic input in the IL. Then we hypothesized that prefrontal dopamine plays a key role in reinstatement and tested this idea. A reminder shock induced c-Fos expression in the IL-projecting dopaminergic neurons in the ventral tegmental area. Blocking of IL dopamine D1 receptor signaling prevented reduction of synaptic input, CeM c-Fos express...
متن کاملThe bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear.
While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear to inappropriate cues leads to a pernicious cycle of avoidance behaviors. Previous studies have revealed large inter-individual variations in fear responding with clinically anxious humans exhibiting a tendency to generalize learned fear to safe stimuli or situations. To shed light on the origin ...
متن کاملApoptosis during sexual differentiation of the bed nucleus of the stria terminalis in the rat brain.
The bed nucleus of the stria terminalis (BST) in the rat forebrain differs between males and females. To test whether apoptosis may contribute to the development of sex differences in the BST, the incidence of apoptosis was determined in sham-treated males and sham-treated females sacrificed on postnatal days (PN) 2, 4, 6, 8, 10, and 12 (PN 1 being day of birth). More apoptotic nuclei were foun...
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ژورنال
عنوان ژورنال: Translational Psychiatry
سال: 2017
ISSN: 2158-3188
DOI: 10.1038/tp.2017.2